Plasticity-driven individualization of olfactory coding in mushroom body output neurons
نویسندگان
چکیده
منابع مشابه
Olfactory representations by Drosophila mushroom body neurons.
Learning and memory has been studied extensively in Drosophila using behavioral, molecular, and genetic approaches. These studies have identified the mushroom body as essential for the formation and retrieval of olfactory memories. We investigated odor responses of the principal neurons of the mushroom body, the Kenyon cells (KCs), in Drosophila using whole cell recordings in vivo. KC responses...
متن کاملActivity of Defined Mushroom Body Output Neurons Underlies Learned Olfactory Behavior in Drosophila
During olfactory learning in fruit flies, dopaminergic neurons assign value to odor representations in the mushroom body Kenyon cells. Here we identify a class of downstream glutamatergic mushroom body output neurons (MBONs) called M4/6, or MBON-β2β'2a, MBON-β'2mp, and MBON-γ5β'2a, whose dendritic fields overlap with dopaminergic neuron projections in the tips of the β, β', and γ lobes. This an...
متن کاملNeural Plasticity: Dopamine Tunes the Mushroom Body Output Network
Two recent studies in Drosophila provide evidence that dopamine can drive synaptic depression and facilitation, supporting models in which learning and the behavioral state of the fly guide behavior by tuning mushroom body output synapses.
متن کاملMushroom body output neurons encode odor-reward associations.
Neural correlates of learning and memory formation have been reported at different stages of the olfactory pathway in both vertebrates and invertebrates. However, the contribution of different neurons to the formation of a memory trace is little understood. Mushroom bodies (MBs) in the insect brain are higher-order structures involved in integration of olfactory, visual, and mechanosensory info...
متن کاملAssociative plasticity and context modulation in GABAergic feedback neurons of the mushroom body output in the honeybee (Apis mellifera)
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ژورنال
عنوان ژورنال: Nature
سال: 2015
ISSN: 0028-0836,1476-4687
DOI: 10.1038/nature15396